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Pharmaceutical Topical Formulation: Creams, Ointments and Gels

Enjoyable, effective, and easy to use ingredients

There is an increasing preference for skin delivery remedies that can be self-applied at home.

Formulators must strive to deliver active ingredients through an exceptional sensory experience to patients of all ages.

CARBOWAX™ SENTRY™ Polyethylene Glycols (PEGs) have a long history of use in topical applications because they meet all compendial requirements and:

  • Are easy to spread
  • Have good sensory perception
  • Can solubilize many active ingredients

Simple formulations can get you started with PEGs today!


CARBOWAX SENTRY for Topical Drug Formulations

Learn how you can maximize your topical drug formulations using CARBOWAX SENTRY Polyethylene Glycols (PEGs).

USP/NF Monograph Ointment Base
  • 60% CARBOWAX™ SENTRY™ PEG 400
  • 40% CARBOWAX™ SENTRY™ PEG 3350

Example compatible APIs: Lidocaine, Mupirocin, Tolnaftate, Benzoyl Peroxide, Acyclovir, Adapalene, Clotrimazole, and more

Emollient Cream
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 3350
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 8000

or

  • 1 – 5% CARBOWAX™ SENTRY™ PEG 400
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 3350
Face or Neck Lotion
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 400
Topical Anesthetic Ointment
  • 55% CARBOWAX™ SENTRY™ PEG 300
  • 40% CARBOWAX™ SENTRY™ PEG 1450
  • 5% Lidocaine
Gels
  • 1 – 15% CARBOWAX™ SENTRY™ PEG 300-8000
Want to prevent yellowing or extend shelf life?
  • Add 0.1 – 1% VERSENE™ NA Edetate Disodium