CARBOWAX™ SENTRY™ Polyethylene Glycol 400 NF, Macrogol 400 Ph. Eur.

What is CARBOWAX™ SENTRY™ Polyethylene Glycol 400 NF, Macrogol 400 Ph. Eur.?

It is a water-soluble linear polymer with an average molecular weight of 400 g/mol. It is a clear, viscous liquid that is easy to handle and ideal for formulations requiring moisture retention, smooth texture, or enhanced solubility. Its terminal hydroxyl groups allow for chemical modification, making it a versatile intermediate in synthesis. Whether developing topical creams, oral solutions, or chemical intermediates, CARBOWAX™ SENTRY™ Polyethylene Glycol (PEG) 400 delivers consistent performance and reliability. INCI Name: PEG-8. Country of Origin: United States of America.

Uses

Pharmaceuticals excipients
Indirect food additives / food contact
Cosmetic ingredients
Personal care ingredients
Chemical intermediates

Benefits

Excellent Solubilizer – Enhances solubility of poorly water-soluble APIs, improving bioavailability.
Versatile Excipient – Acts as a solvent, plasticizer, humectant, and carrier across oral and topical formulations.
High Compatibility – Works well with a wide range of APIs and excipients, supporting flexible formulation design.
Low Volatility – Offers formulation stability due to its low vapor pressure and thermal stability.
Proven Safety – Safe for pharmaceutical use with a well-established safety profile.
Moisture Retention – Functions as a humectant in topical products, helping maintain hydration and product integrity.
Biodegradability – Readily biodegradable based on testing with OECD 301D.