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Blow-Fill-Seal (BFS) Containers
Blow Fill Seal (BFS) Medical Packaging
Dow’s Blow Fill Seal (BFS) containers offer a seamless option for medical and pharmaceutical applications, combining automated aseptic filling with the benefits of squeezability, clarity, and shatter resistance. Our DOW™ HEALTH+™ low-density polyethylene (LDPE) resins help ensure consistent quality and regulatory compliance, adhering to USP Class VI and EU Pharmacopeia standards and offer up to 50% lower extractable levels compared to incumbent offerings. With secure global supply and Drug Master File listings, we can help support your packaging needs from development to delivery.
Polymers for BFS containers
Seamless Aseptic Packaging
Dow’s BFS solutions combine automated aseptic filling with durable, clear, squeezable containers. Made with DOW™ HEALTH+™ LDPE, they address global pharma standards for safety, compliance, and reliability.
That’s where HEALTH+™ comes in.
DOW™ HEALTH+™ Polymers are specially designed to help produce high quality healthcare-related applications. Our successful, pre-approved low-density polyethylene (LDPE) resins for BFS applications help support the product development process.
Why choose Dow’s BFS solutions
Dow’s BFS technology automates filling and sealing in one step, minimizing contamination risk and helping ensure lot-to-lot consistent quality for pharma and healthcare packaging.
Our aseptic packaging maintains sterility and protects sensitive medications. With BFS processes, helps ensure global regulatory and compliance, such USP Class VI, USP 661.1, EU Pharmacopoeia.
Dow BFS materials offerings support accurate single-use dosing, improving patient safety and mitigating risks, while simplifying administration.
Our BFS resins offer increased design flexibility and dimensional accuracy – as well as flexibility, squeezability and clarity. They also allow aseptic filling of precise, pre-measured doses in a fully automated process.
Dow’s LDPE for BFS supports squeezable yet shatter-resistant containers, a good choice for ampoules, vials, intravenous (IV) and other medical and pharmaceutical containers.
Dow provides reliable global supply continuity through multi-site production and robust quality systems. This ensures dependable availability for BFS applications, supported by supply assurance options including 1-year NOC plus 1-year right-to-buy.
Featured Products
DOW™ LDPE 91003 HEALTH+ BFS-Optimized Resin
DOW™ LDPE 91003 HEALTH+™ is a low-density polyethylene resin offering excellent clarity for IV bottles, sterilization up to 108°C supporting faster production, and good processability and structural stability.
DOW™ LDPE 91020 HEALTH+: Aseptic Packaging Solution
DOW™ LDPE 91020 HEALTH+™ Low Density Polyethylene Resin for small ampoules offers excellent clarity and good processability and structural stability.
Dow™ 20 HEALTH+ Series: Ultra-Pure Polyethylene
The Dow™ 20 HEALTH+ Series offers ultra-pure polyethylene resins providing excellent clarity for IV bottles, supports faster production with sterilization up to 112°C, and good processability and structural stability.
DOW™ LDPE 93004 HEALTH+
DOW™ LDPE 93004 HEALTH+ delivers excellent clarity for IV bottles with good processability and structural stability. Its balanced performance supports sterilization up to 112°C, enabling efficient, high-speed production of dependable medical packaging.
Getting the best out of your Blow-Fill-Seal applications
In this webinar, you can hear about the challenges of designing medical and pharma packaging, the benefits of Low Density Polyethylene vs glass, and the properties of DOW™ HEALTH+ resins for medical Blow-Fill-Seal (BFS) applications.
Frequently Asked Questions
BFS technology combines container forming, filling, and sealing in a single automated process. This reduces contamination risk, increases production efficiency, and helps ensure consistent, sterile packaging for sensitive medications, including unit dose applications.
Polyethylene resins, particularly low-density types, offer flexibility, clarity, chemical resistance, and durability. These properties allow containers to be squeezable yet robust, supporting precise dosing while withstanding high-speed BFS processing.
BFS resins are manufactured under strict quality controls, including USP Class VI and EU pharmaceutical standards. Dow maintains consistent molecular properties, purity, and performance through rigorous testing and documentation, helping ensure reliable results in critical medical applications.
BFS is widely used for single-use pharmaceuticals, such as respiratory drugs, ophthalmic solutions, vaccines, and intravenous fluids, and other sterile liquids where contamination prevention and precise dosing are critical.
High-quality BFS resins provide chemical resistance, barrier protection, and shatter resistance. Combined with aseptic processing, these materials protect medications from contamination, maintain sterility, and support safe, reliable delivery to patients.
Together we can raise the bar for innovation, efficiency, performance and safety for BFS containers.
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