Taste Masking

The taste of orally delivered drugs is extremely important to encourage patient acceptability and compliance. Acceptable taste can help to determine market penetration and the commercial success of a new active pharmaceutical ingredient (API) or a new dosage form. Unfortunately, the majority of orally administered, moderately water-soluble drugs are inherently very bitter. This is especially problematic with pediatric suspensions, since children are more sensitive to taste than adults.

With formulations using Dow’s AMBERLITE™ and DUOLITE™ resins, the drug is not released in the mouth so that the patient does not get a bitter taste. For film applications in this space, ETHOCEL™ Ethylcellulose polymers can be customized for greater taste masking functionality due to its water-insoluble nature.

Solutions for Taste Making