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Topical Formulations

Enjoyable, effective, and easy to use ingredients

There is an increasing preference for skin delivery remedies that can be self-applied at home.

Formulators must strive to deliver active ingredients through an exceptional sensory experience to patients of all ages.

CARBOWAX™ SENTRY™ Polyethylene Glycols (PEGs) have a long history of use in topical applications because they meet all compendial requirements and:

  • Are easy to spread
  • Have good sensory perception
  • Can solubilize many active ingredients

Simple formulations can get you started with PEGs today!

USP/NF Monograph Ointment Base
  • 60% CARBOWAX™ SENTRY™ PEG 400
  • 40% CARBOWAX™ SENTRY™ PEG 3350

Example compatible APIs: Lidocaine, Mupirocin, Tolnaftate, Benzoyl Peroxide, Acyclovir, Adapalene, Clotrimazole, and more

Emollient Cream
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 3350
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 8000

or

  • 1 – 5% CARBOWAX™ SENTRY™ PEG 400
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 3350
Face or Neck Lotion
  • 1 – 5% CARBOWAX™ SENTRY™ PEG 400
Topical Anesthetic Ointment
  • 55% CARBOWAX™ SENTRY™ PEG 300
  • 40% CARBOWAX™ SENTRY™ PEG 1450
  • 5% Lidocaine
Gels
  • 1 – 15% CARBOWAX™ SENTRY™ PEG 300-8000
Want to prevent yellowing or extend shelf life?
  • Add 0.1 – 1% VERSENE™ NA Edetate Disodium


Resources

Quick Links

cGMP PEGs
Starting recipes for topical products

cGMP PEGs
Performance and compliance guide