Mother giving daughter medicine
  • Propylene Glycol

DOW PuraGuard™ Propylene Glycol USP/EP offers excellent versatility and functionality in pharmaceutical applications:

  • Solvent and extractant for a wide range of active ingredients, such as corticosteroids, phenol derivatives, barbiturates, vitamins A and D, most alkaloids and many local anesthetics
  • Emollient for softening and smoothing
  • Humectant for promoting moisture retention in skin-care products
  • Coupling agent
  • Plasticizer in aqueous film coating formulations
  • Emulsion stabilizer
  • Dispersant
  • Viscosity modifier

DOW PuraGuard™ PG USP/EP is tested against the specifications of:

  • United States Pharmacopoeia (USP)
  • European Pharmacopoeia (EP)
  • Japanese Pharmacopoeia (JP)
  • Food Chemicals Codex (FCC)

DOW PuraGuard™ PG USP/EP meets the requirements and standards of:

  • Brazilian Pharmacopoeia (FB)
  • U.S. Food and Drug Administration (U.S. FDA)
  • Requirements of pharmaceutical applications worldwide

Dow is the first company to achieve third-party IPEC GMP certification for propylene glycol (PG) from the International Pharmaceutical Excipients Auditing, Inc. (IPEA) for its PG manufacturing facilities in Freeport, Texas, and Plaquemine, Louisiana. In addition, it complies with the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use.

Dow PuraGuard™ PG USP/EP is used in pharmaceutical products as an excipient (non-active ingredient or starting material) or solvent in oral and topical drug products. It is part of a large selection of excipients provided by The Dow Chemical Company.

Dow PuraGuard™ PG USP/EP is approved worldwide for use as a non-active ingredient in pharmaceutical drug formulations.

We recommend consultation of the appropriate regulations or with a qualified advisor for guidance on specific applications.

For Additional Information:

 

Pharmaceutical Industry (392KB PDF)

International Pharmaceutical Excipients Council
IPEC-Americas Inc
U.S. Pharmacopeia

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DOW PuraGuard™: Your Security for Purity (3:34)


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