KATHON™ LX1400 Microbicide for Latex Preservative
KATHON LX1400 microbicide is a formulation for latex emulsions developed following consultations with key customers in this market. It is formulated specifically to meet the changing needs and pressures facing latex emulsion manufacturers.
Product Composition and Typical Properties
The active ingredients of KATHON LX1400 are identified using the IUPAC nomenclature as 5-Chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one.
Reduced Gel Formation/Coagulum
Some latex emulsions are very sensitive to the presence of metal salts and/or organic solvents, forming gels or coagulum when these are introduced. KATHON LX1400 is water based and stabilized with a proprietary combination of stabilizers which greatly reduce gel formation associated with biocide addition. The table below shows examples of gel/coagulum formation tests that compare KATHON LX1400 with other commercially available isothiazolinone formulations. All the data shown is generated using customers' latex emulsions.
This reduction in gel formation presents several advantages to the latex manufacturer:
These are significant advantages which help improve productivity and profitability of production units.
KATHON LX1400 is water based and VOC free.
The stabilizer package of KATHON LX1400 is based upon inert ingredients which are FDA compliant by virtue of being either prior sanctioned, generally recognised as safe (GRAS) or cleared under other existing indirect or direct food additive regulations.
KATHON LX1400 exhibits excellent storage stability with 100% of the active ingredient remaining after 8 and 12 weeks storage at 55°C and 40°C respectively. Other isothiazolinone formulations are not so stable.
In addition KATHON LX1400 offers all the performance benefits associated with other KATHON LX series products.
Broad spectrum activity
Controls both bacteria (Gram-negative and Gram-positive) and fungi (molds and yeasts).
Rapid inhibition of microbial growth and enzyme synthesis
KATHON LX1400 causes immediate inhibition of growth on coming into contact with a microorganism. The growth inhibition rapidly becomes irreversible and results in cell death. Even before cell death occurs, the organism treated with KATHON LX1400 is unable to synthesize enzymes.
Use concentrations are more cost effective than other commercial latex preservatives.
Extensive toxicological testing has shown that the active ingredients of KATHON LX1400 are safe at recommended use levels in your final formulation.
Low use levels
The powerful active ingredients in KATHON LX1400 make it effective at low use levels.
Biodegradable/Non persistent in the environment
Data generated by Dow show that the active ingredients in KATHON LX1400 are readily dissipated in the environment by chemical, biological, and physical means: the products of environmental degradation are easily utilized in biological systems. Active ingredient breakdown does not lead to the presence of chlorinated organics in the environment.
Compatible with surfactants and emulsifiers, regardless of their ionic nature.
KATHON LX1400 does not contain or generate formaldehyde.
Efficacy: Minimum Inhibitory Concentration Data
The table below indicates the minimum concentrations in parts per million (ppm) of KATHON LX1400 which inhibit the growth of various microorganisms in test tube cultures. These data demonstrate broad spectrum anti-microbial activity. The tests are carried out under standardized laboratory conditions in nutrient rich growth media - the MIC concentration will vary according to the growth media used and the test conditions.
Directions For Use
Freshly prepared latex emulsions can be reactive mixtures which makes it difficult to predict accurately the stability and therefore efficacy of a biocide. It is therefore recommended that for each latex emulsion stability and efficacy testing is carried out to optimise biocide dosing.
Extensive laboratory testing and field experience with the product shows that optimal use levels are between 0.01% and 0.02% product as supplied (15 - 30 ppm active ingredient).
KATHON LX1400 has been specially formulated to minimize the need for predilution prior to use.
If you need engineering advice on biocide dosing systems, please contact your Dow representative.
Regulatory Status of KATHON LX1400
The list below is intended to assist you in complying with prevailing regulatory controls. It lists the status of KATHON LX1400 in those countries where specific approval is required.
The preservation of latex emulsions should be achieved through a combination of an effective biocide and good quality control. Biocide addition should not be used to replace good hygiene; it is complementary to good manufacturing practice, not a substitute for it. Some of the key aspects of preventing microbial contamination are given below.
Storage and Handling
Cleaning and Sanitization
Detailed suggestions and guidance regarding plant hygiene are given in our bulletin "Preventing Microbial Contamination in Manufacturing" which is available from your local Dow sales office.
Toxicology and Environmental Fate
Dow takes every measure to ensure that its products are safe for both man and the environment.
In line with this policy, Dow can provide comprehensive toxicological data for KATHON LX1400, which shows it is of low toxicity at recommended use levels. More detailed information on the toxicological profile of KATHON LX1400 can be obtained from your local Dow sales office.
There is no short cut to environmental safety: Dow has conducted extensive research into the environmental fate of the active ingredients of KATHON LX1400.
These studies demonstrate that at normal use/dilution levels KATHON LX1400 has minimal environmental impact because of the following properties:
This combination of properties makes KATHON LX1400 the environmentally sound choice for the preservation of latex emulsions.
Material Safety Data Sheets
Dow maintains Material Safety Data Sheet (MSDS) on all of its products. These contain important information that you may need to protect your employees and customers against any known health and safety hazards associated with our products. We recommend you obtain copies of MSDS for our products from your local Dow technical representative or Dow. In addition, we recommend you obtain copies of MSDS from your suppliers of other raw materials used with our products.
Use biocides safely. Always read the label and product information before use.
KATHON is a trademark of Dow, or of its subsidiaries or affiliates.
These suggestions and data are based on information we believe to be reliable. They are offered in good faith, but without guarantee, as conditions and methods of use of our products are beyond our control.
We recommend that the prospective user determines the suitability of our materials and suggestions before adopting them on a commercial scale.
Suggestions for uses of our products or the inclusion of descriptive material from patents and the citation of specific patents in this publication should not be understood as recommending the use of our products in violation of any patent or as permission or license to use any patents of Dow.
For further details, please contact your local Account Manager or local Business Representative.
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