Some active pharmaceutical ingredients (APIs) are sensitive to the effects of heat, light and oxygen. Dow offers solutions to protect APIs from environmental conditions and increase the stability of the ingredients in liquid suspensions to guarantee a drug’s long-term quality, efficacy and safety.
Solutions for API Stability
METHOCEL™ products can be used as thickeners, binders, film-formers and for water-retention in a number of pharmaceutical applications. METHOCEL™ products increase the stability of liquid suspensions.
CARBOWAX™ SENTRY™ PEGs and MPEGs
CARBOWAX™ SENTRY™ PEGs and MPEGs are used in the synthesis of pharmaceutical actives such as diesters, carbonates, carbamates. They are also used to prepare hydrophilic foams and rheology modifiers based on urethane chemistry.
Liquid suspensions such as antibiotics, insulin and vaccines are produced through a series of separation and purification steps. Dow’s AMBERLITE™ resins can enable high performance purification and separation operations.
By creating a stable amorphous form, AMBERLITE™ resins can also prevent polymorphism which occurs when drugs change from one crystalline or amorphous form to another.