Dow Excipients

Products

Three polymer chemistry choices cover a wide range of formulation variables. Complying with FDA and USP/NF requirements, these products have been used in pharmaceuticals for decades. They are essentially tasteless, colorless, odorless, nonionic, and noncaloric. This unusual combination of properties makes them useful for pharmaceutical formulations.

These products meet the requirements of the Food Chemicals Codex, the International Codex Alimentarius and/or US Pharmacopoeia (USP) or National Formulary (NF). Premium cellulose ether products can also meet the requirements of Japanese, British, and European Pharmacopoeias.

FOR CONTROLLED RELEASE PHARMACEUTICAL PRODUCTS

The alliance between Dow and Colorcon for the global marketing, sales, technical service and development, and distribution of Dow pharmaceutical excipient products for use in controlled release applications is our answer to the global pharmaceutical industry’s demand for faster development and more efficient production of drug ingredients.

Click here to see the specific METHOCEL™, ETHOCEL™ and POLYOX™ controlled release pharmaceutical products available through Colorcon. This alliance is being implented by geography in 2007.

DOW EXCIPIENT PRODUCTS
Product Chemical Type Viscosities Available, cps
ETHOCEL™ Standard Premium Ethylcellulose NF1 4; 7; 10; 20; 45; 100
ETHOCEL™ Standard FP Premium Ethylcellulose NF1 7; 10; 100
METHOCEL™ A Premium Methylcellulose USP2 15; 400; 1,500; 4,000
METHOCEL™ E3 Premium Hypromellose 29102 3; 5; 6; 15; 50; 4,000; 10,000
METHOCEL™ F Premium Hypromellose 29062 50; 4,000
METHOCEL™ K4 Premium Hypromellose 22082 3; 100; 4,000; 15,000; 100,000
POLYOX™ Water-Soluble Resins NF Grade Poly(ethylene oxide) NF 30-50 (5% solution)
55-90 (5% solution)
600 – 1,200 (5% solution)
8,800-17,600 (5% solution)
2,000 – 4000 (2% solution)
1,650 – 5,500 (1% solution)
5,500 – 7,500 (1% solution)
7,500 – 10,000 (1% solution)

1NF (current)
2USP (current)
3METHOCEL™ E Premium products are also available in CR (controlled release)  grades for 4,000 and 10,000 cps products ensuring consistent performance
4METHOCEL™ K Premium products are also available in CR (controlled release)  grades for 100, 4,000, 15,000 and 100,000 cps products ensuring consistent performance
Viscosities for METHOCEL™ Premium products are for 2% solutions in H2O at 20°C
Viscosities for POLYOX™ Water-Soluble Resins, NF Grade are for aqueous solutions at 25°C at concentrations noted above

Other Dow Sites
Beyond excipient polymers, The Dow Chemical Company offers a very wide array of additional products and services for the pharmaceutical industry, including raw materials, process chemicals, processing aids, films and packaging materials, separation and purification technologies, and development and manufacturing services for the pharmaceutical and biopharmaceutical industries.


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