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With more products moving from pilot to commercial-scale production, the biopharmaceutical industry demands buffers and biochemicals in larger quantities. Building on its global leadership of TRIS AMINO™ Tromethamine, ANGUS Buffers & Biochemicals (ABB), a subsidiary of ANGUS, fulfills the developing need to help customers reduce raw material and supply chain costs by providing biological buffers, biochemicals and diverse sourcing capabilities for the life science industry.

 

TRIS AMINO Tromethamine from ANGUS is used in a wide variety of pharmaceutical, ophthalmic and other life science applications, where it serves as a synthesis or analytical buffer, neutralizer, solubilizer and stabilizer. TRIS AMINO is a mildly alkaline chemical compound with a molecular weight of 121.14. Its chemical structure is that of a trihydric alcohol, which also possesses primary amine functionality. TRIS AMINO is readily water-soluble (up to 80 g/100 mL water) and possesses alcohol and glycol solubility. It is also known variously as tromethamine (USP, INCI, and CTFA), tris buffer, THAM or trometamol.

 

ANGUS is the inventor, and currently world’s leading manufacturer, of TRIS AMINO™ Tromethamine products with production and packaging facilities in Sterlington, LA, and Niagara Falls, NY, in the United States, and in Ibbenbüren, Germany. ANGUS is the world’s only back-integrated manufacturer of TRIS AMINO products for life sciences that comply with GMP; and TRIS AMINO Ultra PC Tromethamine which is compliant with current global government regulations for personal care and cosmetics products.

 

As bioprocessing continues to evolve and production and commercialization scale continue to increase, compliance during sourcing and supply chain requirements will become more complex. ANGUS Buffers and Biochemicals can meet these increasingly rigorous supply chain demands for cell culture media suppliers, diagnostic kit manufacturers and biopharma companies.

 

With a manufacturing process that complies with GMP, and ISO 9001:2000 certified production and packaging facilities, ANGUS Buffers & Biochemicals personnel are committed to delivering the highest-quality products and services to customers requiring commercial quantities. ANGUS Buffers and Biochemicals can also provide additional resources, including special testing, custom blending, specialized packaging and ERP connectivity. 

 

For more information on the buffers and biochemicals chemistry visit the Amino Alcohols page or tell us about your application through the Contact Us form.